Alzheimer Treatment and Very Effective Cure for Alzheimer

Alzheimer's disease is the most common cause of dementia, affecting around 465,000 people in the United Kingdom. 'Dementia', the term describes a set of symptoms that may include memory loss, mood swings and problems with communication and reasoning. These symptoms occur when the brain is damaged by certain diseases and conditions, including Alzheimer's disease. This fact sheet describes the symptoms and risk factors for Alzheimer's disease, and describes what currently available treatments.

Alzheimer's disease, first described by German neurologist Alois Alzheimer, is a physical disease affecting the brain. During the course of the disease, 'plaques' of protein and "tangles" develop in the structure of the brain, leading to the death of brain cells. People with Alzheimer's also have a shortage of some important chemicals in the brain. These chemicals are involved in transmitting messages within the brain.

Alzheimer's is a progressive disease, which means that gradually, over time, more parts of the brain are damaged. As this happens, the symptoms are more severe.

Symptoms

People in the early stages of Alzheimer's disease may experience lapses of memory and have trouble finding the right words. As the disease progresses, you can:

1. Confused and often forget the names of people, places, appointments and recent events

2. Experience changes in mood, feeling sad or angry, or frightened and frustrated by their memory loss increasing.

3. Increasingly withdrawn, either due to a loss of confidence or communication problems

4. Have difficulty performing daily activities - could be confusing to verify your change in shops or become unsure how to work the TV remote.

As the disease progresses, people with Alzheimer's need more support from those who care for them. Over time, all you need assistance with daily activities.

Although there are some common symptoms of Alzheimer's disease, it is important to remember that each person is unique. No two people are prone to Alzheimer's disease in the same way.

Mild cognitive impairment

Recently, some doctors have begun using the term mild cognitive impairment (MCI), when a person has trouble remembering things or thinking clearly, but the symptoms are not severe enough to warrant a diagnosis of Alzheimer's disease. Recent research has shown that people with MCI have an increased risk of developing Alzheimer's disease.

However, the conversion rate from MCI to Alzheimer's disease is low (about 10-20 percent each year), and therefore a diagnosis of MCI does not always mean that the person will develop Alzheimer's disease.

What causes Alzheimer's disease?

So far, no single factor has been identified as a cause of Alzheimer's disease. It is likely that a combination of factors, including age, heredity, environmental factors, lifestyle and health in general, are responsible. In some people the disease can develop silently for years before symptoms appear.

Age

Age is the biggest risk factor for dementia. Dementia affects one in 14 people age 65 and one in six over 80 years. However, dementia is not limited to the elderly: in the UK, more than 16,000 people under 65 with dementia, although this is probably an understatement.

Heredity

Many people fear that they may inherit Alzheimer's disease and scientists are investigating the genetic background of Alzheimer disease.

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We know there are a few families where there is a clear legacy of the disease from one generation to the next. This is often in families where the disease appears relatively early in life.

In most cases, however, the influence of genes inherited from Alzheimer's disease in the elderly appears to be small. If a parent or other relative has Alzheimer's disease, your chances of developing the disease are only slightly higher than if there were no cases of Alzheimer's disease in the immediate family.

For more information, see our fact sheet on genetics and dementia (405).

Treatment

There is currently no cure for Alzheimer's disease. However, drug treatments available that can temporarily relieve some symptoms or slow its progression in some people.

People with Alzheimer’s disease have shown that there is a shortage of acetylcholine in the brain. The drugs Aricept, Exelon and Reminyl (trade names for drugs donepezil hydrochloride, rivastigmine and galantamine) work for the maintenance of existing supplies of acetylcholine. From March 2011, these drugs are recommended as an option for people in the stages of mild to moderate Alzheimer's disease.