MTHFR Gene Mutation

What is the MTHFR Gene Mutation?

Have you ever wondered why individuals are so similar but yet significantly different? Well, as human beings we possess genes that vary from each. This might be substantially the reason why one human may be very fit throughout his/her years while the falls ill frequently. Health conditions are significantly related to the presence of a faulty gene referred to as the Methylenetetrahydrofolate Reductase (MTHFR). This component is essential in the function of the process of methylation that regulates gene expression. Methylation is critical for various processes within the body; therefore, it affects different health conditions.

The presence of MTHFR mutations may result in severe issues to the body. The main ways it can affect your body is through the immune system by lowering the body’s ability to produce the essential element glutathione. This component serves as the bodies main detoxifier and antioxidant. Significant reduction of this vital nutrient may result in lesser tolerance of toxic exposures in addition to premature aging and stress.

Why should one be tested?

According to various study results, more than 80% of the earth’s population has either mutation of the MTHFR gene (C677T and A1298C). The MTHFR C677T can result in high homocysteine. Such mutations of this particular allele can lead to a significant impact on health as compared to others. Nonetheless, MTHFR A1298C has not been clinically identified to have any effects on one's homocysteine levels. However, this allele has a significant impact on the production of tetrahydrobiopterin.

Compound homozygous and heterozygous C677T is considered to be at risk of severe methylation malfunction. Considering the high-risk factor of homocysteine to numerous diseases, MTHFR testing is essential for individuals. When the compound heterozygous MTHFR mutations relate to each other, they are highly likely to increase the risk of a heart attack.

Some people are usually born with the MTHFR within their body that result in lower functioning of the MTHFR enzymes. Owing to their direct impact on methylation to which it affects our health, such mutations may place an individual at a higher risk of developing health problems such as thyroid disease, cancer, congenital disabilities, migraines, heart issues, and miscarriages.

To help you determine whether you suffer from the MTHFR mutations here’s are some of its symptoms

• Frequency in gastrointestinal issues- Individuals that have had constant recurring gastrointestinal matters are most likely to contain the MTHFR mutation
• Long-standing depression and anxiety is a sign of MTHFR mutation.
• Cardiac family history- If you have had recurring family history on dementia or cardiac problems, there is a possibility you might be suffering from the MTHFR mutation
• Folate deficiency
• High homocysteine levels

If you have experienced either of the issues above, it is essential to get a consultation from an MTHFR gene mutation specialist. By getting a gene mutation test done on you, you can then determine whether you require the treatment. For ease, MTHFR testing is done by a simple cheek swab. After you are diagnosed with the type of MTHFR you have, you can quickly proceed with the appropriate MTHFR treatment process.