Articles and studies 

 

Golf performance enhancement by means of 'real-life neurofeedback' training based on personalized event-locked EEG profiles (in press) Martijn Arns, Michiel Kleinnijenhuis, Kamran Fallahpour & Rien Breteler. Journal of Neurotherapy

 

Electroencephalographic, personality and executive function measures associated with frequent mobile phone use. (2007) Martijn Arns, Gilles van Luijtelaar, Alex Sumich, Rebecca Hamilton & Evian Gordon. International Journal of Neuroscience

 

Different Brain activation patterns in Dyslectic chrildren: Evidence from EEG ower and coherence patterns for the double-deficit theory of Dyslexia. (2007) Martijn Arns, Sylvia Peters, Rien Breteler & Ludo Verhoeven. Journal of Integrative Neuroscience

 

Rates of Decline Distinguish Alzheimer's Disease and Mild Cognitive Impairment relative to Normal Ageing Integrating Cognition and Brain Function (2007) Belinda Liddell, Rob Paul, Martijn Arns et al. Journal of Integrative Neuroscience

 

Habituation effects on somatosensory event-related potentials (SEPs) elicited by painful electrical stimuli (2006) C.M. van Rijn, M.L.A. Jongsma, E. van den Broeke, S. Postma, R. van der Lubbe, J.R. Buitenweg, M. Arns, R. Quian Quiroga, H. van Goor, M. Luckers, et al. European Journal of Pain, 10(1), S72

 

Patterns of Cognitive Performance in Middle-Aged and Older Adults: A Cluster Analytic Examination. (2006) Gunstad, Paul, Brickman, Cohen, Arns, Rowe, Lawrence & Gordon. Journal of Geriatric Psychiatry and Neurology, 19, (2), 59-64.

 

Effects of different Biofeedback training procedures on quantitative Electroencephalographic parameters of healthy subjects. (2006) Martijn Arns, Erica Heesen, Desiree Spronk, Michiel Kleinnijenhuis & Rien Breteler. BIAL grant 2004.

 

EEG Markers for Cognitive Decline in Elderly subjects with subjective memory complaints. Alexander D.M., Arns M.W., Paul R.H., Rowe D.L., Cooper N., Esser A.H., Fallahpour K.,Stephan B.C.M, Heesen E., Breteler R., Williams L.M., Gordon E. Journal of Integrative Neuroscience, Vol. 5, No. 1 (2006):49-74.

 

The validity of 'IntegNeuro': A new computerized and standardized battery of neurocognitiv tests. Paul R.H., Lawrence, J., Williams, L.M., Clark, R.C., Cooper, N. & Gordon, E. (2005) International Journal of Neuroscience, 115, 1549-1567

 

Long term EEG and Psychometric effects of mobile phone use
Martijn Arns, Gilles van Luijtelaar, Rebecca Hamilton & Evian Gordon
Presented at the Human Brain Mapping Meeting 2004, Poster TH4.

 

Standardized assessment of cognitive functioning during development and ageing using an automated touchscreen battery  Clark C.R., Paul R.H., Williams L.M., Arns M., Fallahpour K., Handmer C. & Gordon E. (2006). Archives of Clinical Neuropsychology, 449-467.

 

The development of a hybrid outdoor FES bike. Rik Berkelmans, Martijn Arns, Jacques Duysens (2003) IFESS meeting, Sydney.

 

Excitotoxic hippocampal lesions disrupt allocentric spatial learning in mice: effects of strain and task demands
Arns M., SauvageM. & StecklerT. (1999). Behavioural Brain Research, 106, 153 - 166 ( KB).

 

rTMS or magnetic Brain stimulation is a new method to treat depression as an alternative to antidepressants. After more then 20 years of research and the first results from the clinic, this treatment seems very efficacious without any adverse side effects. Transcranial Magnetic Stimulation (rTMS) is part of a new development in the treatment of psychiatric disorders, where more often treatments are more focal, localised and personalized. Besides rTMS other treatments such as Deep Brain Stimulation and EEG Biofeedback are also part of this new development; also referred to as Personalized Medicine. The primary goal of Personalized Medicine is to get the right treatment to the right person at the right time, leading to higher efficacies and fewer side effects.

 

In the Brainclinics Treatment clinic in Nijmegen (The Netherlands) rTMS has been applied over the last year in a practical setting and combined with psychotherapy. In this setting any client with depression is treated (so not only treatment resistive patients). The rTMS treatment is personalized for every client using their individual QEEG on the basis of which the stimulation site is chosen. Furthermore, the EEG is used to rule out contra-indications – such as paroxysmal activity and the presence of beta spindles.

 

The First preliminary conclusions can summarized as follows: 
1)     After 20 sessions 9 out of 10 patients – 90% showed a full remission, meaning they had a BDI score lower then 13.
2)     Within 15 sessions of rTMS treatment patients showed a more then 65% reduction in depressive symptomatology (BDI score).
3)     During these sessions no adverse side effects were reported.
4)     Forty percent of these patients were free of medication and 60% was on antidepressant medication before the treatment was initiated. Some clients were even able to lower their medication doses during treatment.
5)     In addition to these 10 patients, 1 was excluded due to contra-indications and there was 1 drop-out.
6)     At this moment more data is being collected and we envision the complete data-set will be available in the 2nd quarter of 2008. However, these preliminary results look most promising!  In comparison, Antidepressants such as Citalopram show full remission in maximum 33% of patients (Trivedie et al., 2006; STAR*D trial) and only 30-50% of clients respond well to Antidepressant medication.

Martijn Arns
Psycholoog NIP / Director

Brainclinics
Bijleveldsingel 34

6524AD Nijmegen, The Netherlands

Tel: +31 (0)24-7503505
GSM: +31 (0)6-48177919

E-mail: Martijn Arns