Excipients play an indispensable role in the process of pharmaceutical preparation. Disintegrants are added to a formulation to promote the drug release. To make disintegrant excipients easily accessible for scientists and researchers, Formulationbio recently announced that it now provides a wide range of disintegrant excipients that are frequently used in pharmaceutical research.
The disintegrants allow the fast breakdown of the dosage form in the stomach upon ingestion. The underlying mechanism of action is that: once coming into contact with moisture such as water, disintegrants will help tablet formulation to rapidly break up.
Disintegration is the de-aggregation of particles within tablets upon exposure to aqueous fluids and it is typically viewed as the first step in the dissolution process. After that, the active pharmaceutical ingredient becomes bioavailable and is readily absorbed. There are two classes of disintegrants, namely, traditional disintegrants and super disintegrants. The most popular and commonly used super disintegrants are: croscarmellose sodium, crospovidone, and sodium starch glycolate.
The disintegrant excipients provided at Formulationbio include (just to name a few here):
KICCOLATE Croscarmellose Sodium, PC-10 Pregelatinized Starch, Ludiflash, Primellose Croscarmellose sodium, Primojel Sodium starch glycolate, Solani Amylum Native potato starch, SuperStarch 200 Partly pregelatinised maize starch, CD - Sodium Starch Glycolate, RetaLac, Tablettose 100, Extra white maize starch, Maize Starch, CD Flash mannitol-starch for orodispersable tablets, Potato Starch, STARLAC lactose-starch, STARLAC lactose-starch compound, Wheat Starch TB and many more.
In addition to disintegrant, Formulationbio also offers binder excipients, filler excipients, lubricant excipients, sweetener excipients, coating systems excipients, emulsifier excipients, lipid excipients, taste masking excipients, solubilizer excipients, active pharmaceutical ingredient excipients, carrier excipients, compaction excipients, dry powder inhalation excipients as well as other types of excipients for pharmaceutical research. For more information, please visit: https://www.formulationbio.com/products/disintegrant-excipients.html.
About Formulationbio
Staffed with a group of pharmaceutical experts, including Chemists, Biochemists, Engineers, and highly qualified operators, Formulationbio not only supplies a wide range of excipients, but also works closely with the pharmaceutical industry as a contract service organization, offering outstanding expertise to handle complex formulations.