Alfa Chemistry, a global supplier of chemical products and services, has recently expanded its lineup of derivatization reagents for High-Performance Liquid Chromatography (HPLC). Derivatization is a crucial step in HPLC analysis, especially in the detection of triterpenoids, where enhancing performance and sensitivity is of utmost importance.

HPLC is a widely used analytical technique in various industries, including pharmaceuticals, environmental testing, and food and beverage quality control. It separates, identifies, and quantifies components in a mixture based on their interactions with a stationary phase and a mobile phase.

Derivatization is a crucial step in the HPLC process, as it involves the chemical modification of analytes to improve their detectability and separation characteristics. By using derivatization reagents, researchers can overcome the limitations of traditional HPLC methods and achieve superior results in terms of peak resolution, signal intensity, and detection limits.

“For instance, triterpenoids are a class of compounds characterized by their complex structures and diverse functions. They are often found in natural products, such as plant extracts and herbal medicines, making them challenging to analyze using conventional HPLC methods,” said the Marketing Chief of Alfa Chemistry. “In this regard, derivatization reagents play a key role in improving the detectability and sensitivity of triterpenoids, ultimately leading to more accurate and reliable results.”

Alfa Chemistry's expanded range of derivatization reagents includes acyl chlorides, sulfonic esters, amines, and other functional groups designed to target specific sites on triterpenoids, such as -OH and -COOH groups. By using these reagents, researchers can enhance the performance of their HPLC separations and achieve better sensitivity, ultimately leading to more comprehensive and detailed analysis results.

"We understand the challenges faced by researchers in the analysis of complex compounds like triterpenoids. That's why we are continually expanding our range of derivatization reagents to meet the evolving needs of the scientific community," the Marketing Chief further added.

Alfa Chemistry's derivatization reagents are meticulously tested and validated to ensure their purity, consistency, and reliability in HPLC applications. The company also offers technical support and custom synthesis services to assist researchers in finding the right reagents for their specific analytical needs.

Currently, the following derivatization reagents are available for HPLC applications: Methyl 3,5-diformyl-1-indolizinecarboxylate (CAS 163556-04-5), 2-Anthracenesulfonyl chloride (CAS 17407-98-6), 4-Nitro-7-piperazinobenzofurazan (CAS 139332-66-4 ), Aminoferrocene (CAS 1273-82-1), Fusaric acid (CAS 536-69-6), Europium sulfate hydrate (CAS 10031-55-7), Cyanoacetamide (CAS 107-91-5), (CAS ), Ferrocenecarboxaldehyde (CAS 12093-10-6), Dimedone (CAS 126-81-8), and more.

With the addition of new derivatization reagents to its product lineup, Alfa Chemistry continues to solidify its position as a leading supplier of chemical solutions for HPLC analysis. Researchers and scientists can now access a wider range of reagents to enhance the performance and sensitivity of their HPLC separations, ultimately leading to more accurate and reliable results in their research endeavors.

Please visit to learn more.

Author's Bio: 

During the past decade, Alfa Chemistry has made every endeavor to solidify its role as a trust-worthy supplier of various chemicals and materials. To this end, its product offering has been constantly enriched, providing scientists and researchers with a broader range of options.