Best Way To Treat High Blood Pressure

Amlodipine is a long-acting calcium channel blocker used as an anti-hypertensive and as the treatment of angina. Amlodipine acts by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance and hence reducing blood pressure in angina it increases blood flow to the heart muscle.

Anginia is sort chest pain which primarily cause by the lack of oxygen supply in the body and also due to the lack of waste removal from the body. It is an obstruction or in some cases spasming of the coronary artery which are the heart's blood vessels. There can be severe chest pain to a certain subject due to extensive lack of oxygen but it will not in turn cause a heart attack. At its worst stages, angina attacks have been reported to last at over 15 minutes in subjects. In most cases patients have reported to have discomfort in their chest rather than actual pain, unsual discomfort such as tightness, heaviness, pressure has been reported in the chest by many patients. These are all considered as signs of anginia.

Old age (55 above), cigarette smoking, diabetes mellitus, kidney disease, obesity are the various altrications which in turn result in Anginia. Roughly 6.3 million american's have been reported to have diagnosed with Anginia.

The drug in qusetion which in Amlodipine, acts by relaxing the smooth muscles which are present in the arterial wall of the heart, which eases the severe chest pain. The contraction of the heart muscles depends upon the movement of extra-cellular calcium ions into the cells present in the smooth heart muscles, Amlodipine acts by selectively allowing the calcium ions into the arterial walls and therefore easing the chest pain by maintaining smooth heart contraction.

This medicine can be obtained via a prescription and there are some minor side-effects reported while consuming this specific drug. They can be charcterized by their frequency in which they affect the patients :

Very Often - Fatigue, peripheral edema.

Often - dizziness, palpitations, muscle stomach or headache, dyspepsia, nausea.

Sometimes - blood disorders, development of breasts in men (gynecomastia), impotence, depression, insomnia, tachycardia, gingival enlargement - in 1 in 1,000 users,

Rarely - erratic behavior, hepatitis, jaundice - in 1 in 10,000 users

Very rarely - hyperglycemia, tremor, Stevens–Johnson syndrome - in 1 in 100,000 users

If the dosage of this specific drug increased in patients with severe heart disease it can result in increasing heart problems and can also cause heart attack in very rare occasions.

Excessive lowering of blood pressure during initiation of amlodipine treatment can occur, especially in patients already taking another medication for lowering blood pressure. In rare instances, congestive heart failure has been associated with amlodipine, usually in patients already on a beta blocker.