New research suggests strategies to overcome technological limitations to more accurately detect PMS2 – a genetic mutation which plays a role in Lynch syndrome which can lead to colorectal cancer (more commonly known as colon cancer). This can help better diagnose cases of colon cancer and offer more effective treatment.

Lynch syndrome is a hereditary colorectal cancer susceptibility syndrome. Blood relatives of those with Lynch syndrome have a 50 percent chance of developing cancer. PMS2s role in Lynch syndrome has been greatly underestimated due to technological limitations.


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