Wegener's granulomatosis (granulomatosis with polyangiitis) is a disease characterized by damage to small vessels, with the formation of specific granulomas, in various organs and systems of the human body. In this article, we are going to discuss what Granulomatous with Polyangiitis is, and how we can manage this disease with the help of Ayurveda. With proper care and treatment, one can live a happy and comfy life for a prolonged time.

What is Granulomatous with polyangiitis?

Granulomatous with polyangiitis formerly known as GPA or Wegener's Granulomatosis.  It is a systemic granulomatous-necrotizing vasculitis of small-caliber vessels, with a predominant lesion of the upper respiratory tract (URT), lungs and kidneys, associated with antineutrophilic cytoplasmic antibodies (ANCA). GPA is considered to be a relatively rare disease.

What is ANCA?

ANCA has associated vasculitis (AAV) is a group of systemic autoimmune diseases characterized by inflammatory necrotizing lesions of the walls, predominantly small (capillaries and venules) and, much less often, middle vessels of various organs, as well as the frequent presence of antineutrophilic cytoplasmic autoantibodies (ANCA) in the blood serum.

Primary AAV includes:-

  • Granulomatosis with Polyangiitis (GPA).
  • Microscopic Polyangiitis (MPA).
  • Eosinophilic Granulomatosis with Polyangiitis (EGPA).
  • ANCA-associated vasculitis with isolated kidney damage.

Causes of Granulomatous with Polyangiitis

The cause of Granulomatous with Polyangiitis (GPA) is not known. It is not a contagious disease. It doesn’t occur within families.

Symptoms of Granulomatous with polyangiitis

The classic picture of Wegener's granulomatosis includes the following symptoms:

  • Pain in the musculoskeletal system, Joint Pain.
  • General Weakness, headache, fever.
  • Necrotic and dystrophic processes in the organs of granulomatosis.
  • Hoarseness, cough.
  • frequent nosebleeds;
  • Increased sweating at night;
  • Numbness of the hands;
  • Diseases of systems and organs are characteristic (pleurisy, renal failure, liver cirrhosis).
  • Loss of appetite.
  • Dizziness.
  • Blood in the urine.

Differentiating indicators, which clearly indicate the presence of Wegener's granulomatosis, is damage to the upper respiratory tract, lungs, and kidneys.

There are 4 stages of development of Wegener's granulomatosis

Stage I

Rhinogenic Granulomatosis

Stage II

Pulmonary - accordingly, necrotic-ulcerative lesions of the lungs are involved in the process of pathogenesis, secondary inflammation is formed.

Stage III

Generalized lesion –A direct generalization of the pathological process, diseases of the kidneys, blood vessels, organ of vision, etc.

Stage IV

Terminal - the development of respiratory and renal failure, which is not compatible with human life.

There is also a limited form of the disease, without kidney damage. However, such cases occur in 15-20%. If the kidneys are involved in the process, then noticeable changes in the body immediately occur hematuria (blood in the urine), back pain, proteinuria (a significant amount of protein in the urine).

Unfortunately, at the moment, mortality due to Wegener's granulomatosis is quite high, which is due to the late diagnosis of the disease and the subsequent complete destruction of the respiratory system and kidneys.

Complications in Granulomatous with polyangiitis

  • Deafness.
  • Development of necrosis throughout the body.
  • Destruction of the bones of the hands, adrenal insufficient.

Therefore, you need to take care of yourself, treat each disease from beginning to end. The period of remission in patients is no more than six months.
Granulomatosis can be provoked by many processes in the body:

  • Taking hormonal drugs.
  • Viral infections (influenza and measles, scarlet fever, adenoviruses and herpes viruses, Epstein-Barr).
  • Ionizing radiation.
  • The intake of chemicals (benzene) and immunosuppressant can also provoke this disease.

Who is more prone to Granulomatous with polyangiitis?

The disease can affect all organs, but the most common targets are the upper and lower respiratory tract, as well as the kidneys. GPA usually develops in middle-aged and older people (40–50 years), equally in men and women. The disease often develops in girls during adolescence. The average age of patients at the time of the onset of the disease does not exceed 40 years.

Diagnostics for Granulomatous with polyangiitis

Methods for diagnosing granulomatosis include the processes of searching for antigens, on their own cells, as well as factors of rheumatism (C - reactive protein).

Instrumental methods are used to locate foci and apply local therapy. This therapy uses the X-ray method to examine and search for parts or foci that are affected by granulomatosis.

Wegener's granulomatosis

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Ayurvedic Treatment for Granulomatous with Polyangiitis

Ayurveda is the science of a healthy and fulfilling life, it is not only a medical but also a philosophical system. It is focused on the achievement of harmony by every person, “continuous happiness” and considers a person as a part of the Universe, which is in the closest mystical relationship with it. Ayurveda keeps many secrets - ancient Indian medicine, philosophy, way of life, "science of being", "science of longevity". Fundamental in Ayurveda is the aspect of the "subtle anatomy" of a person. This is its main difference from other wellness practices.

According to Ayurveda, Granulomatous with polyangiitis occurs due to the imbalance of Tridoshas: - Vata, Pitta, Kapha. Vata is responsible for movement, Pitta is responsible for Digestion and transformation and Kapha dosha represents the structure and Lubrication of the body. When these tridoshas are in balance, our human body cast health. The individual feature of each dosha is expressed from its positive side. So Planet Ayurveda is here to treat Granulomatous with polyangiitis with Herbal remedies.

Planet Ayurveda provides the best herbal remedies for Ayurvedic Treatment of Wegener's Granulomatosis. Our herbal medicine contains excellent quality herbs that are devoid of any kind of side effects. These remedies are prepared by strictly following the ancient principles of Ayurveda. Herbal Remedies of Planet Ayurveda are 100% pure, natural, and vegetarian. All medicines are free from any kind of color, chemical, and additives. These herbal remedies are safe to use at any age.

Product Description

1. Curcumin Capsules

These capsules are prepared by using the ancient principle of Ayurveda. Curcumin (Active compound of Turmeric) is traditional medicine in Ayurveda, Siddha, and Unani system. Curcumin Capsules provide strength to the immune system. These capsules help in preventing cancers, tumors as it has healing property. They help in purifying blood. These capsules are antiseptic by nature.

Dosage: - 2 capsules twice a day, with normal water, after a meal.

2. Tulsi Capsules

Tulsi capsules are prepared by using a standardized extract of Tulsi (Ocimum sanctum). Tulsi plant is helpful in fighting infections against different pathogens in an effective manner. These capsules work as a natural immune modulator. Tulsi capsules are helpful in allergy, Diabetes, Auto-immune disorder, cancer, chronic rhinitis, and autoimmune disorder.

Dosage: - 1 capsule twice a day, with plain water, after a meal.

3. Septrin Tablets

Septrin tablets are prepared by using different powerful herbs. These tablets are very beneficial in balancing tridoshas of the body. Some major ingredients used in septrin tablets are Guggul (Commiphora mukul),Haldi (Curcuma longa), Tulsi (Ocimum sanctum), Sonth (Zingiber officinale), Marich (Piper nigrum), and Pippali (Piper longum). These tablets support the respiratory and immune systems with a Healthy Digestive system. These are also beneficial in reducing weight and cholesterol levels.

Dosage: - 2 capsules twice a day, with plain water, after a meal.

4. Kishore guggul tablets

Kaishore guggul is one of the most effective Herbal Remedy for Gout. These tablets are mainly useful for the accumulation of pitta dosha which indicates pain and inflammation. The Major ingredients of Kaishore guggul are Amalaki (Emblica officinalis), Bibhitaki (Terminalia bellirica), Haritaki (Terminalia chebula), Guggul (resin) (Commiphora mukul), Guduchi herb (Tinospora cordifolia). These herbs provide relief from motion sickness, high cholesterol, gout, liver disorders. These tablets can be beneficial for treating ailments like severe pain and inflammation.

Dosage: - 2 capsules twice a day, with plain water, after a meal.

5. Suvarna Basant Malti Ras

These tablets are herbal mineral formulation. It is prepared under strict medical supervision as it contains various heavy metal. These tablets are useful in treating problems like weakness, nervous debility, diabetes, cataract and repeated infections. These tablets contain herbs like Swarna bhasma (incinerated form of gold), Mukta bhasma (incinerated form of gold), Sudhahingula (purified cinnabar), Maricha (Piper nigrum), Kharpara bhasma (incinerated form of calamine), Bhavanadrava:nimbuswarasa(lemon juice). These herbs work as insulin modulator, vitalizer, and Hormonal balancer.

Dosage: - 2 capsules twice a day, with plain water, after a meal.


Granulomatosis is a systemic, necrotic disease that affects the vessels of the respiratory system, kidneys, liver, and other organs. It is one of the rare diseases that can occur to anyone. However, before panic begins to rise, it's important to grasp various ways to uplift our well-being on our own with the assistance of the Ayurvedic regime. So, Planet Ayurveda Herbal Medicines will help you in providing Treatment of Granulomatous with Polyangiitis by balancing the constitution of the human body.

Author's Bio: 

Dr. Vikram Chauhan (MD-Ayurveda) is an expert Ayurvedic Doctor based in Chandigarh, India, and doing his practice in Mohali, India. He is spreading the knowledge of Ayurveda - Ancient healing treatment, not only in India but also abroad. He is the CEO and Founder of Planet Ayurveda Products, Planet Ayurveda Clinic, and Krishna Herbal Company. For more info visit our website: www.planetayurveda.com