Inoculation against small-pox and snake-bite were performed by rubbing the contents of a pustule into an incision in the skin. In the long process of discovering which plants are edible, humans in the Stone Age also identify many which seem to cure ailments or soothe a fever. ‘Venesection’ was performed on various veins. Even a difficult and severe operation as ‘Trephining’ of the skull was performed by the primitive men as early as the Stone Age.

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In India, primitive medicinal practices included the process of discovering which plants are edible. Humans in the Stone Age also identified many which seem to cure ailments or soothe a fever.