The key to optimal monetization model selection

The key concept to wrap your mind around when it comes to picking ways your blog will make money is the fact that different niches have different optimal monetization opportunities. Pay attention to the word "optimal." While almost all blogs can feature an Adsense, ad blocks, some niches perform better on Adsense while other niches do terribly. You have to focus on optimizing how you're going to make money off your blog. You don't want to put yourself in a situation where you trying to put a square peg into a round hole says the magazine http://pcmate.org
You can jam Adsense ads on your website. No problem there.
However, be prepared to live with very little money. You would probably be better off if you had picked a different monetization model. It all boils down to your niche.
This is where it gets tricky. You can take guesses but it is going to take a lot of time and a lot of lost opportunities for you to finally get a clear idea as to which monetization models work and don't work for your website. Your better approach would be to reverse engineer your competition. Regardless of what niche you're in, chances are very high somebody is already there before you.
Don't get sad about this. In fact, this should make you happy.

Why?
They're doing their homework for you. If they're featuring certain ads and you know that these blogs are the top blogs in your niche and they've been around for a while, you know at some level or other, their monetization model is working for them. Pay attention to the monetization models used by competing blogs in your niche. If you notice that a lot of them used Adsense,
then chances are, Adsense should be your first option.
If you notice that a lot of them used CPA ads, then this may be the way to go.

Regardless of how they make their money, pay attention to their monetization model. At the very least, this gives you a clear idea as to which monetization models to experiment with. This doesn't mean that you're going to stick with that particular way of making money but it's definitely much better than rolling the dice and taking shots in the dark and hoping to get lucky.