Vitamin C Regulates Stem Cell Function

If you suffer from joint pain and mobility issues, stem cell therapy can help and does so without invasive surgery. Stem cell therapy can work when more conventional treatments such as narcotics and steroids do not. It’s safe and effective. Nearly one-third of Americans suffer from some type of chronic pain and countless people end up having joint replacement surgery. Instead of pain management or temporary relief provided by more conventional treatments, stem cell therapy can repair the connective tissue and stimulate the growth of tendons, ligaments, cartilage and even bone. Stem cells have been shown to promote lasting pain relief and perhaps more significantly, they promote restoration of normal mobility.

Stem cell therapy basics

Stem cell therapy helps tissues to heal naturally and rebuild. When injected, the cells divide and restore cells that have been harmed by normal wear-and-tear, joint injury, or illness. Stem cell or cord blood contains growth factors, “cytokines” and stem cells that work together to enable the formation of a rich microenvironment that supports the regeneration of tissue and cellular growth. This also allows the body’s natural healing ability to work. As we age, our natural stem cells are depleted and aren’t as effective. This is why therapies such as stem cell treatments have emerged. Also, they have properties that help the body’s natural immune system minimize pain and control pain and muscle inflammation and improve circulation. In addition to its efficacy, stem cell therapy has also grown increasingly popular because it is not invasive, but is safe and promotes soft tissue regeneration and has no real adverse side effects.

Stem cell therapy has been used more than 60,000 times in the US, and no bad side effects have been no reported. The therapy has a 100% safety record in Europe, where more than 100,000 people have been treated. Donors are tested under the panels of infectious disease that are more stringent than the government requires. Donors also go through intensely rigorous screening by the Food and Drug Administration and the American Association of Tissue Banks and all cells are documented and tested to FDA requirements.

The role of vitamin C in stem cell therapy

Vitamin C is an important dietary requirement for humans. In addition to its known role as an antioxidant, vitamin C is a cofactor for Fe2+- and α-ketoglutarate-dependent dioxygenases (Fe2+/α-KGDDs), which make up a large number of enzymes. Vitamin C can modulate stem cell function, enhance reprogramming of helpful stem cells, and slow down the unwanted replication of the undesirable hematopoietic stem cells by being able to promote the activity of the good stem cells called Jumonji C (JmjC) domain-containing histone demethylases and ten-eleven translocation DNA hydroxylases. Something called epigenetic dysregulation is a known driver of malignancy, and vitamin C may play a novel role as an epigenetic anticancer agent. Research shows Vitamin C supports the growth of good stem cells and may "tell" faulty stem cells in the bone marrow to mature and die normally, instead of multiplying to cause blood cancers. Clinics such as NAD Stem Cell around the country specialize in stem cell treatments.

The metabolism of stem cells has historically been difficult to study because a large number of cells are required for analysis, while stem cells in each tissue of the body are rare. Techniques developed during the study, which was published in Nature, have allowed researchers to routinely measure metabolite levels in rare cell populations such as stem cells.

Vitamin companies are now formulating private label vitamins with high dosage vitamin C compounds as special supplements for those undergoing stem cell treatment.

Looking to the future, there is also a significant interest in the role of stem cells and vitamin C play in human neuropathology.