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- 4 Ways To Choose The Best Pediatric Dental Specialist - by Submitted on Jun 05, 2020 from Rudds jamesAll parents are concerned about taking our children to the dentist and even more if it is our child's first visit. Children must attend their pediatric dental exams from an early age, so the more comfortable the little one can be in this visit, the better they will be the following. You ...
Views: 11 - Home insurance: why are the rates so random? - by Submitted on Jun 05, 2020 from James SmithPerson A has pretty good credit and has never filed claims on his home insurance. Person B has pretty good credit and has never filed claims on his home insurance. You might think that a quote from the same company on home insurance would produce similar, if not identical, results, right? Unless ...
Views: 11 - Alcohol Rehabilitation Centre - by Submitted on Jun 05, 2020 from Mousumi ChangAlcohol addiction is considered an alarming condition. This type of addiction can lead to violent behavior, relationship problems, property or job loss, and a lot more. With this, a certain alcohol addict needs to seek the help of an alcohol rehab centre. To know more about it, read on. The ...
Views: 12 - Breast Implants: Its Important Types And Procedures For Treatment - by Submitted on Jun 05, 2020 from Kumar AbhinavAs a woman, you can get breast implants to make your breast bigger and fuller. There may be many reasons why one wants to get breast implants. The medical term for it is known as breast augmentation, and you will find some of the Best Breast Augmentation Surgeon in Camarillo. The surgical ...
Views: 14 - Halitosis – Top Facts Must Know - by Submitted on Jun 05, 2020 from Kumar AbhinavBad breath negatively impacts approximately 25 percent of the demographic. Many times it ensues while speaking to someone with bad breath we got uncomfortable but feel awkward to say that their breath fumes.Bad breath is worrisome and causes public humiliation and dignity questions. What Is ...
Views: 17 - All About Cleaning Services For Residential and Commercial Purposes - by Submitted on Jun 04, 2020 from Amit KumarRemember the last time you took a rain check and cleaned up your house! Don’t you love that feeling and positive energy that comes from a de-cluttered and clean house? However, managing work, as well as the household tasks, can take a toll on your life. So, what can be done? The right move ...
Views: 40 - Different Methods of Eye Bag Removal Surgery - by Submitted on Jun 04, 2020 from M Nasir AzizDo you often wonder how you can get rid of the nuisance eye bags that seem not to be going away? It's time to consider eye bag removal surgery. Family history or poor lifestyle choices often contribute to this menace in a significant way. If the eye massage, altering the sleeping position, or ...
Views: 26 - Here Are What You Should Know About Hifu facelift - by Submitted on Jun 04, 2020 from M Nasir AzizAs you grow and age up, your skin tends to appear unsightly due to the formation of wrinkles, fine lines and sagging. To regain your younger-looking and radiant skin, some people consider getting the hifu. It was primarily used for the treatment of tumors initially. It was later discovered by ...
Views: 26 - Mind Over Circumstances: How to Stay Emotionally Healthy While in Self-Isolation - by Submitted on Jun 04, 2020 from M Nasir AzizThere is no doubt that we are living through challenging times. Although the word "pandemic" was relegated to fictional stories and films in the past, it has now become a part of our daily vocabulary. Many of us have been impacted by changing employment concerns as well as being forced to remain ...
Views: 31 - What are Kratom Leaves and how do they affect the body? - by Submitted on Jun 04, 2020 from Marina PalKratom leaves are a tropical tree that belongs to the coffee family. Kratom (Mitragyna speciose) is commonly found in Thailand, Myanmar, Malaysia, and other South Asian countries. Leaves or kratom leaf extracts are generally used as stimulants and sedatives. This leaf is also said to treat ...
Views: 23 - 7 Best Tips Before and During Your Appointment with a Gynaecologist in Singapore - by Submitted on Jun 03, 2020 from Marina PalFor most women, revealing reproductive healthconcerns to a physician can be challenging. That is why they should build a good relationship with agynaecologist or at least be prepared to talk about their most intimate concerns, fertility issues, pregnancy, family planning, and other related women ...
Views: 27 - Why Don’t Bats Get Affected by Coronavirus? - by Submitted on Jun 03, 2020 from Ada BrownAbout 85% of people with new coronavirus infection show mild or moderate symptoms, but about 15% can progress to severe disease, and 5% of them will eventually develop acute respiratory distress syndrome, septic shock or multiple organ failure. Why does the same pathogen infection make different ...
Views: 23 - Alpaca and 2019 Novel Coronavirus (2019-nCoV) Pneumonia - by Submitted on Jun 03, 2020 from Ada BrownWith the global pandemic of novel coronavirus (2019-nCoV) pneumonia raging, most countries in the world have already entered strict control. Before the vaccine has been fully developed, the best way for a country to control the epidemic is to urge people not to go out and stay at home to cut off ...
Views: 21 - Proteolysis-Targeting Chimeras as Tools in Drug Development (III) - by Submitted on Jun 03, 2020 from Ada Brown3.2. Off-target protein degradation Multiple studies have shown that PROTACs are not entirely selective and can degrade proteins other than the primary target. Degradation of a protein that is not directly bound by the PROTAC can arise as a consequence of “bystander degradation” where the ...
Views: 21 - Proteolysis-Targeting Chimeras as Tools in Drug Development (II) - by Submitted on Jun 03, 2020 from Ada Brown2.2. The second generation small molecular PROTACs 2.2.1. The MDM2-based PROTAC The first all-small molecule-based PROTAC, overcoming the major defects of the first generation, such as higher molecular weight, poor cell permeability, and poor stability, was consisted of the MDM2 ligand ...
Views: 26 - Proteolysis-Targeting Chimeras as Tools in Drug Development (I) - by Submitted on Jun 03, 2020 from Ada BrownProteolysis targeting Chimera (PROTAC) has been emerged by hijacking the endogenous ubiquitin-proteasome system (UPS) to specifically degrade protein of interests (POI) in 2001. PROTAC are drug-like molecules that induce the degradation of proteins, and they work by tightly binding E3 ligases ...
Views: 19 - Principles and Main Steps of Homology Modeling - by Submitted on Jun 03, 2020 from Ada BrownThere are three main methods for protein structure prediction: homology modeling, folding recognition and de novo calculation. All those methods are used to predict unknown protein structures. Since the amino acid changes generally occur in the inflection region on the surface of the protein, ...
Views: 17 - What You Need to Know About the Coronavirus - by Submitted on Jun 03, 2020 from Ada BrownAbstract: As the novel coronavirus is spreading rapidly and threatening many countries in the world, knowing more about coronavirus may help you overcome your panic. Just in the first 3 months of 2020, the Words of the Year has already found its candidate – coronavirus. People who have pets ...
Views: 19(1 vote) - The Research and Application Progress of Transcriptome Sequencing Technology (III) - by Submitted on Jun 03, 2020 from Ada Brown3.6. Mutation detection By analyzing the transcriptome sequencing data, you can obtain sequence information for all transcripts of the sample, including all SNP and Indel mutation types on the transcript. The RNA molecules generated by transcription may undergo various modifications before ...
Views: 17 - The Research and Application Progress of Transcriptome Sequencing Technology (II) - by Submitted on Jun 03, 2020 from Ada Brown1.5. Full transcription sequencing The transcription level of mRNA is affected by the regulation of lncRNA, small RNA and circRNA. Quantitative analysis of biomolecular networks and regulatory pathways in cells or specific tissues in a certain space-time requires quantitative and qualitative ...
Views: 19 - The Research and Application Progress of Transcriptome Sequencing Technology (I) - by Submitted on Jun 03, 2020 from Ada BrownTranscriptomics is a discipline that systematically studies gene transcription profiles from the overall transcription level and reveals the molecular mechanisms of complex biological pathways and trait regulatory networks. Before the development of high-throughput sequencing technology, ...
Views: 13 - Introduction to Cancer Bioinformatics - by Submitted on Jun 03, 2020 from Ada BrownCancer is a disease caused by some genetic and epigenetic changes. In its simplest form, cancer is a genetic disease caused by a cell genome change which includes point mutation, insertion mutation, deletion mutation and chromosome translocation. At present, the basic research of cancer is ...
Views: 11 - Will Severe Asthma Be the Next Hot Antibody Drugs (II) - by Submitted on Jun 03, 2020 from Ada BrownImmunoglobulin E (IgE) As mentioned above, IgE plays an important role in the asthma inflammatory response pathway, especially for the onset of allergic asthma. In 2003, Novartis' IgE antibody, omalizumab (trade name Xolair) entered the market as the first antibody drug against asthma, ...
Views: 13 - Will Severe Asthma Be the Next Hot Antibody Drugs (I)? - by Submitted on Jun 03, 2020 from Ada BrownAbout Omalizumab Omalizumab was first FDA approved in 2003 to treat adults and children 12 years of age and older with moderate to severe persistent allergic asthma which is not controlled by inhaled steroids. Since its U.S. approval, more than 200,000 patients older than 12 with allergic ...
Views: 15 - The Future of Gene Therapy Used for Complex Diseases - by Submitted on Jun 03, 2020 from Ada BrownIntroduction As early as in 1972, the famous American biologists Friedmann and Roblin has put forward the concept of gene therapy in Science magazine. Gene therapy in a broad sense refers to the use of molecular biology methods to introduce target genes into patients, to express them, ...
Views: 14 - The Challenge of Gene Therapy - by Submitted on Jun 03, 2020 from Ada BrownGene therapy for genetic diseases refers to the application of genetic engineering techniques to introduce normal genes into the cells of patients to correct the defects of the disease-causing genes and eradicate the genetic diseases. The way of correction can be to repair the defective gene in ...
Views: 15 - Introduction to Advenovirus Vector - by Submitted on Jun 03, 2020 from Ada BrownThe advenovirus Adenovirus is the non-enveloped double-stranded DNA, and the genome contains approximately 26-48 kbp. It was first isolated in the 1950s, but it was not until the 1980s that the therapeutic potential of adenovirus as a gene delivery vector was discovered. Adenovirus is the ...
Views: 13 - Exosome – Small but Mighty Player in Immune System - by Submitted on Jun 03, 2020 from Ada BrownAbstract: Exosomes released by immune cells can participate in various immune system-related activity and disease development by transporting substances such as proteins, lipids, mRNA and miRNA. Since being founded, exosomes have been considered as a cell waste for many years, but recently, ...
Views: 17 - An Overview of the Relationship Between Complement System and Autoimmune Diseases (II) - by Submitted on Jun 03, 2020 from Ada Brown3.3 Dermatomyositis Inflammatory myopathy is a group of acquired diseases characterized by inflammatory cell infiltration of skeletal muscle and muscle fiber necrosis, usually manifested as moderate to severe muscle weakness and infection, mainly including polymyositis, dermatomyositis and ...
Views: 14 - An Overview of the Relationship Between Complement System and Autoimmune Diseases (I) - by Submitted on Jun 03, 2020 from Ada BrownComplement system Complement is a type of protein in human and vertebrate serum and tissue fluid that is activated and has biological activity and can mediate immune and inflammatory reactions. Soluble proteins, regulatory proteins and related membrane proteins (receptors) and other ...
Views: 15 - An Overview of Phosphor Specific Antibody - by Submitted on Jun 03, 2020 from Ada BrownWhat is a phosphorylated antibody? Antibodies produced against a phosphorylation site in the state of phosphorylation and dephosphorylation of a substrate, so that the phosphorylation and dephosphorylation of the substrate and the change in antibody binding type are used to investigate ...
Views: 13 - A Guide to the Establishment and Development of Yeast two-hybrid System - by Submitted on Jun 03, 2020 from Ada BrownAutomatic protein expression quantitative analysis system The establishment of the two-hybrid system is due to the understanding of the transcription initiation process regulated by eukaryotes. Initiation of cell gene transcription requires the participation of trans-transcription ...
Views: 17 - A Promising Method to Realize Faster and More Accurate Diagnosis on SARS-CoV-2 - by Submitted on Jun 03, 2020 from Ada BrownThe current global concerns are caused by a new coronavirus strain never found in human body before, belonging to β genus, which is highly infectious and can be transmitted by droplets, contact and aerosols. International Committee on Taxonomy of Viruses entitled it as Severe Acute Respiratory ...
Views: 14 - Treatment of Skin Conditions Using Chemical Peels - by Submitted on Jun 01, 2020 from Marina PalYears of sun exposure and breakouts can make your skin tone uneven, appear dull, and result in hyper pigmentation. Sometimes your skin might not respond positively to over-the-counter skin products, and it might be best if you seek chemical peels skin treatment. An esthetician should evaluate ...
Views: 30 - Learning More about Battle Born Bone - by Submitted on Jun 01, 2020 from Marina PalTo maintain a healthy physique and musculoskeletal system, you need to get the help of a certified orthopedic physician. At Battle Born Bone & Joint Center, you can get a diagnosis and treatments for your musculoskeletal system. Dr. Jaymes Granata and his team deliver personalized care, ...
Views: 36 - 9 Powerful Ways to Stay Safe from Coronavirus - by Submitted on Jun 01, 2020 from medplus martCoronavirus is the current buzz all over the world. But is it really worth all the fear especially in India? According to data, Coronavirus has taken the lives of 3,200 people across the world and infected over 1,00,000 people across the world with a majority of 90,000 in China and around 30 in ...
Views: 23 - Yoga Pillow - by Submitted on May 30, 2020 from sidd mktYoga is an exercise that can be easily done at home with no major requirement of big machines like while gymming. Yoga involves various body postures, breathing exercises, meditation, etc. Yoga helps in rejuvenation of both body and mind. Although yoga involves minimal use of props but there are ...
Views: 37 - Alcohol Abuse Specialist at LifeSync Malibu, California - by Submitted on May 28, 2020 from Marina PalExcessive consumption of alcohol affects the quality of your life and health. If you are unable to quit drinking alcohol or can’t make it through the day without getting a drink, you need help to regain control of your life. LifeSync Malibu is making a significant effort in addressing the ...
Views: 45 - WHAT’S THE DIFFERENCE BETWEEN AN ENZYME PEEL AND A CHEMICAL PEEL? - by Submitted on May 27, 2020 from Mousumi ChangGetting a peel is highly recommended by professionals as a part of your skincare routine. Peels are a type of exfoliation that encourages turnover of cells in your skin. This helps your skin regenerate safely and heal to get rid of dead skin cells, dullness, and damage caused by free radicals. ...
Views: 41 - The 12 Best Things About Medical Negligence Claims - Medical Negligence Direct - by Submitted on May 26, 2020 from Zuzu CodesSometimes it can be difficult to know whether the illness or injury you suffered was as a result of medical negligence, or it was a consequence of something else. Medical Negligence is a complex part of law, but with the right knowledge, you can make the best decisions for your health and ...
Views: 51 - Demystifying Health and Wellness - by Submitted on May 25, 2020 from Akbar AliThe rigmarole of daily life may at times feel like mundane drudgeries, like running on the treadmill with all your might and still having no destination to reach to. Life comes with its fair share of stress and trials. Yes, those moments can be frustrating and we need to cool off steam, almost ...
Views: 54 - THE BEAUTY OF BEING A MEDICAL SCRIBE - by Submitted on May 25, 2020 from Marina PalAnyone in the medical profession can attest to working long hours and being on tight schedules in the course of their career. Despite this, the medical profession has its perks. If medicine is a career you want to explore, it is wise to gain as much information as possible. One of the best ways ...
Views: 58 - What is menopause and how long does menopause last? - by Submitted on May 28, 2020 from Marina PalDuring the menopause, the hormone balances of the body change. The ovaries produce less and fewer sex hormones. It takes an average of five to ten years for the organism to adapt to the new hormone levels. During this time, the symptoms typical up to menopause such as hot flushes, a dry vagina ...
Views: 75 - How Long Does It Take CBD to Start Working? - by Submitted on May 24, 2020 from Marina PalHow fast does CBD oil work? It’s a question that many people have once they decide that they’d like to try CBD for the first time. Of course, understanding how quickly you’ll experience potential benefits is only part of the story. You’re also probably curious to learn about things like how long ...
Views: 67 - Components of Laser Resurfacing - by Submitted on May 24, 2020 from Marina PalIt is not an easy task to maintain a clean and healthy skin. At Skin Deep Laser MD, we are dedicated and committed to walking with our clients every step of the way in their quest to sustain flawless skin. We are your go-to Fort Worth physician whenever you want to find high-quality services ...
Views: 47 - Heart Conditions: All about Peripheral Arterial Diseases - by Submitted on May 24, 2020 from Marina PalYour heart is your life, right? Most people will often want to take care of their heart health at all times, which is valuable. However, sometimes things will go beyond our abilities, and experts will have to come in. Perhaps such would be the ideal time for you to visit an expert to help with ...
Views: 51 - The Basics of Botox - by Submitted on May 24, 2020 from Marina PalFor a reason, you feel that you are not beautiful enough. Perhaps you convinced yourself that your skin is not as youthful as you so desire or that it is too saggy for your liking. All these are possible, and you are not alone. However, does that mean that you should lose hope? Most likely not. ...
Views: 45 - Why Are We Waiting for a Vaccine to Save Us? - by Submitted on May 22, 2020 from Janeska Smith-AsantePersonally, I’m not waiting for a Vaccine. Even though, talking heads on TV are constantly PUSHING the idea that we have Some SUPER People…somewhere coming up with the MIRACLE answer to all our problems. Really? That’s not something we should just BLINDLY believe. When there’s someone I CAN ...
Views: 62 - 5 Signs You May Be Suffering From a Hormonal Imbalance - by Submitted on May 22, 2020 from Katie GordenThere are several symptoms that could indicate hormonal imbalance, so it's hard to know whether you're dealing with your hormones or another health issue. Hormones affect all the systems and cells in the body and some imbalances in hormone levels can be very severe and significant affect your ...
Views: 81 - How to Treat Your Kid's Cavity When They Can't See a Dentist - by Submitted on May 22, 2020 from Katie GordenIt doesn't matter if you're a kid or an adult, no one likes getting cavities, and these days, most of us are under stay-at-home orders in the state we live. Our dentists are not seeing patients for check-ups and any other non-essential dental care until those executive orders are lifted. That ...
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